Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

Neural pathways reveal a push-pull system for coordinating goal-directed behavior in mice

Most of the tasks that humans complete daily entail carefully coordinating movements and tracking progress made toward a ...