sourmash is a tool for biological sequence analysis and comparisons. sourmash compare and sourmash plot produce basic distance matrix plots that are useful for comparing and visualizing the ...
Distortions from traditional dimensionality reduction methods obscure relationships in high-dimensional single-cell data, thus impeding biological insights. We introduce DTNE (diffusive topology ...
These scripts can be used to cluster a parsed set of monomeric protein chains via a global conformational change metric based on CA distances. Once the polypeptide chains destined for clustering have ...
F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) is a robust imaging modality used for staging multiple myeloma (MM) and assessing treatment responses. Herein, we ...
Haplotype identification, characterization and visualization are important for large-scale analysis and use in population genomics. Many tools have been developed to visualize haplotypes, but it is ...
EpiScanpy is a toolkit for the analysis of single-cell epigenomic data, namely single-cell DNA methylation and single-cell ATAC-seq data. To address the modality specific challenges from epigenomics ...
Natural phenomena are teeming with temporal complexity, but such dynamics, however fascinating, offer substantial obstacles to quantitative understanding. We introduce a general method based on the ...
Statistical machine learning methods are increasingly used for neuroimaging data analysis. Their main virtue is their ability to model high-dimensional datasets, e.g., multivariate analysis of ...
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